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Staff Machine Learning Engineer

GeneDx Inc

GeneDx Inc

Software Engineering
Posted on Sunday, June 9, 2024

Staff Machine Learning Engineer

GeneDx is seeking an exceptional Staff Machine Learning Engineer / AI Engineer to spearhead the development of generative AI applications to automate aspects of genetic testing business. In this role, you will leverage your expertise in Large Language Models (LLMs), machine learning, and product development to create a generative AI system for automating genetic test writing, insurance claim reports, clinical document understanding, and/or literature mining and recommendations.


  • Independent Project Leadership: Take the lead in architecting and developing a state-of-the-art ML pipeline or agent-based system that utilizes LLMs and context-aware tools to generate genetic test reports.
  • Project Management: Manage small project-specific teams to develop and maintain data preprocessing, feature engineering, and model training pipelines.
  • Research and Development: Research, evaluate, and implement various LLMs and ML techniques to optimize the system's performance and output quality independently.
  • Collaboration: Collaborate with the clinical staff to incorporate domain-specific knowledge and ensure the accuracy and relevance of the generated reports.
  • NLP Techniques Implementation: Independently implement advanced NLP techniques such as named entity recognition, sentiment analysis, and text summarization to enhance report generation.
  • Performance Monitoring and Improvement: Independently monitor, analyze, and improve the system's performance based on user feedback and advancements in ML and LLM technologies.
  • ML Infrastructure Development: Contribute independently to the development of a robust, scalable, and secure ML infrastructure.
  • Other Duties: Independently handle other duties as assigned.


  • Advanced Degree: Advanced degree in Computer Science, Machine Learning, or a related field.
  • Experience: Extensive experience in developing and deploying ML/AI-based systems independently.
  • Technical Skills: Strong independent expertise in Python, natural language processing (NLP), and large language models (LLMs).
  • LLM Libraries: Experience with LLM libraries such as LangChain, Llama Index, Instructor, DsPy, Outlines, or Instructor.
  • Vector Databases: Experience with Vector Databases such as Chroma, Weaviate, PineCone.
  • Deep Learning Frameworks: Proficiency in deep learning frameworks such as TensorFlow, PyTorch, Keras, HuggingFace.
  • Additional Skills: Experience with fine-tuning LLMs, Kubernetes, model serving technologies, ML experiment tracking (e.g., CometML, Weights and Biases).
  • Soft Skills: Excellent problem-solving, analytical, and communication skills. Ability to work independently in a fast-paced, innovative environment.
  • Domain Knowledge: Knowledge of genetics or experience in the healthcare domain is a plus.

Pay Transparency, Budgeted Range
$229,581$275,494 USD


Science - Minded, Patient - Focused.

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most.

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.


From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:


  • High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
  • Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.


  • Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
  • Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
  • Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.


Benefits include:

  • Paid Time Off (PTO)
  • Health, Dental, Vision and Life insurance
  • 401k Retirement Savings Plan
  • Employee Discounts
  • Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.